Super-Resolution Imaging with OEK Chip Technology

Breaking the resolution barrier with our innovative OEK chip platform, enabling unprecedented visualization of DNA-gold nanoparticle conjugates for biomedical applications.

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Core Technology Advantages

Our OEK chip platform offers unique capabilities that set it apart from conventional imaging technologies

Ultra-High Resolution

2-4x resolution improvement over traditional microscopy, enabling clear observation of 50nm nanostructures

Integrated Platform

Combines microsphere lens technology, ODEP manipulation, and OEK chip functionality in a single system

Label-Free Imaging

High-contrast imaging without fluorescent labeling, simplifying experimental workflows

Microfluidic Compatible

Seamless integration with microfluidic systems for high-throughput automated detection

Precise Manipulation

Non-contact ODEP technology enables precise manipulation without physical damage

Fast Imaging

Rapid imaging capabilities for real-time observation of dynamic biological processes

Technology Platform

Our innovative platform integrates three core technologies to deliver unprecedented imaging capabilities

OEK Chip Technology

Microsphere Lens Technology

Utilizes high refractive index microspheres to collect and convert non-diffracted light from samples into propagating light waves, breaking the resolution limit of traditional optical microscopy.

  • 2-4x resolution improvement
  • Simple implementation
  • Compatible with standard microscopes

Optically-Induced Dielectrophoresis (ODEP)

Employs non-contact micro-manipulation technology to safely and precisely position microsphere lenses on regions of interest, combine with scanning microscopy to achieve quick large area super-resolution imaging.

  • Non-contact manipulation
  • Low power requirement (1W/cm²)
  • Large area super-resolution imaging
Super-Resolution Imaging
Gold Nanoparticle Applications

Opto-Electrokinetic (OEK) Chip

Innovative microfluidic-compatible chip design that enables precise control and patterning of gold nanoparticle-biomolecule conjugates, providing a stable platform for super-resolution imaging.

  • Sandwich structure design
  • Light-controlled electrode array
  • Multi-functional integration

Market Opportunity

Significant growth potential in biomedical imaging and nanotechnology markets

$32.15B
Biosensor Market by 2033
10.4%
Annual Growth Rate
$321.2M
Gold Nanoparticle Market by 2033
12%
Nanoparticle Annual Growth
Biomedical Market Growth

Competitive Advantage

vs. Traditional Super-Resolution Techniques

  • Lower cost and complexity compared to STED and STORM/PALM
  • No labeling requirements for high-contrast imaging
  • Faster imaging speeds for dynamic processes
  • Full microfluidic compatibility

vs. Existing Gold Nanoparticle Manipulation

  • Superior precision with non-contact manipulation
  • Zero sample damage during operation
  • Real-time monitoring capabilities
  • Integrated manipulation, fixation, and imaging

Application Areas

Our technology has broad applications across biomedical research and clinical diagnostics

Biomedical Detection

Biomedical Detection

High-resolution observation of disease biomarkers and cellular structures

  • Disease biomarker detection
  • Single-cell analysis
  • High-sensitivity diagnostics
Drug Development

Drug Development

Real-time observation of drug-receptor interactions and delivery systems

  • Drug-receptor interaction analysis
  • Drug delivery system evaluation
  • High-throughput screening
Basic Research

Basic Research

Advanced tools for studying nanobiointerfaces and molecular interactions

  • Nanobiointerface research
  • Molecular interaction mechanisms
  • Single-molecule imaging
Clinical Diagnostics

Clinical Diagnostics

Early disease detection and precision medicine applications

  • Early disease diagnosis
  • Precision medicine
  • Point-of-care testing

Technical Achievements

Key breakthroughs in our research and development efforts

Non-contact Microsphere Positioning System

Developed a system using ODEP forces for precise manipulation and positioning of microsphere lenses, eliminating imaging interference from traditional cantilever structures.

Super-Resolution Imaging in Microfluidic Environment

Successfully achieved super-resolution imaging within microfluidic environments, laying the foundation for integrated bioanalytical systems.

Gold Nanoparticle Patterning Technology

Established precise patterning and fixation of gold nanoparticles using the electrophoretic effect of the OEK platform, facilitating subsequent super-resolution observation.

DNA-Gold Nanoparticle Conjugate Observation

Achieved high-resolution imaging of 50nm and 100nm gold nanoparticles in label-free state, providing new tools for biomolecular interaction research.

Development Roadmap

Our strategic plan for technology advancement and commercialization

Technology Optimization

Continuous improvement of core technology capabilities

  • Resolution enhancement below 50nm
  • Increased imaging speed for real-time observation
  • Reduced phototoxicity with optimized ODEP parameters
  • Multi-modal imaging integration

Function Expansion

Broadening the scope of applications and capabilities

  • 3D super-resolution imaging development
  • Deep tissue imaging capabilities
  • Portable device design for field applications
  • AI-assisted image analysis integration

Market Strategy

Strategic approach to commercialization and market penetration

  • Academic collaborations for technology validation
  • Industry partnerships for product development
  • Technology licensing to equipment manufacturers
  • Startup incubation for accelerated commercialization

Investment Value & Cooperation

Attractive investment opportunity with clear path to commercialization

Investment Value

Compelling reasons to invest in our technology

  • Large market size with double-digit growth rates
  • High technical barriers with integrated platform
  • Broad application prospects across multiple fields
  • Clear commercialization path from research to clinical

Cooperation Models

Flexible partnership opportunities

  • Technology licensing to equipment manufacturers
  • Joint product development for specific applications
  • Research collaborations for novel applications
  • Investment partnerships for accelerated growth

Expected Returns

Projected timeline for return on investment

  • Short-term (2-3 years): Revenue through licensing and research equipment
  • Mid-term (3-5 years): Scale-up with diagnostic products and services
  • Long-term (5-10 years): Significant returns as technology penetrates precision medicine market

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